Engineering News
November 3 , 2003, Vol. 74, No. 11F

BioE BRILLIANCE: Tejal Desai has successfully tackled some of the most challenging research issues in her BioE field. As a Ph.D. at Cal she developed an internal insulin regulator for rats.

BioE alum named by Popular Science Magazine as one of its annual “Brilliant 10”

At age 31 Tejal Desai (BioE ’98)is not only a celebrated professor in Boston University’s BioE department, but has been recognized by Popular Science magazine for her work in diabetes, medicine delivery, and artificial blood vessel research. The magazine named her one of this year’s “Brilliant Ten.”

Desai’s Ph.D. project at Cal was to build an implantable device to eliminate the daily insulin injections diabetics give themselves to control blood sugar levels. Her colleagues warned her the task was too hard and that she would never graduate, but she proved them wrong.

“Six or seven years ago, when I started the project, it was unknown to merge micro- and nanotechnologies with human cells or biological entities. No one knew if it was functional. Now it’s a hot topic,” she says.

After spending four years coaxing cells to grow on chemically modified silicon surfaces, Desai could implant a microscopic device in rats that delivered ongoing, regular doses of insulin. The product is currently being developed by a private company for human use.

Desai also developed a speck-sized layered plastic device that attaches to the intestinal lining and releases medicine. Next, she plans to tackle artificial blood vessels. Her goal is to make artificial vessels that help the body generate replacements, then biodegrade, leaving the new natural vessels behind.

Desai knew she wanted to be an engineer since high school, when she heard a biomedical engineer speak about building artificial organs and artificial limbs for people with spinal cord injuries.

“I went into academia to combine my interest in research, teaching, and policy. I can work with companies, government and patients. It encompasses everything,” she adds.

For more on Desai’s research go to bme.bu.edu/faculty/desai.html


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